Combined low-dose everolimus and low-dose tacrolimus after Alemtuzumab induction therapy: a randomized prospective trial in lung transplantation

Combined low-dose everolimus and low-dose tacrolimus after Alemtuzumab induction therapy: a randomized prospective trial in lung transplantation

Abstract Background Long-term outcomes of lung transplantation are severely affected by comorbidities and development of chronic rejection. Among the comorbidities, kidney insufficiency is one of the most frequent and it is mainly caused by the cumulative effect of calcineurin inhibitors (CNIs). Cur...

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Bibliographic Details
Main Authors: Alberto Benazzo, Ara Cho, Anna Nechay, Stefan Schwarz, Florian Frommlet, Thomas Wekerle, Konrad Hoetzenecker, Peter Jaksch
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Trials
Subjects:
Lung transplantation
Alemtuzumab
Induction therapy
Everolimus
Kidney function
Immunotolerance
Online Access:https://doi.org/10.1186/s13063-020-04843-9

Internet

https://doi.org/10.1186/s13063-020-04843-9

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