Thermal analysis of ligand-DNA interaction: determination of binding parameters
The review discusses the methods of thermodynamic analysis of reactions of non-covalent binding of biologically active compounds with DNA, which is a key constituent of cell chromatin. Knowledge of thermodynamic profile of ligand binding with nucleic acids is important for understanding the mechanis...
Main Authors: | Ekaterina Bereznyak, Natalia Gladkovskaya, Evgeniy Dukhopelnykov, Anastasiya Gerus, Anastasiya Lantushenko, Maxim Evstigneev |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2015-09-01
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Series: | AIMS Biophysics |
Subjects: | |
Online Access: | http://www.aimspress.com/biophysics/article/410/fulltext.html |
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