Molecular Tug of War Reveals Adaptive Potential of an Immune Cell Repertoire

The adaptive immune system constantly remodels its lymphocyte repertoire for better protection against future pathogens. Its ability to improve antigen recognition on the fly relies on somatic mutation and selective expansion of B lymphocytes expressing high-affinity antigen receptors. However, this...

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Bibliographic Details
Main Authors: Hongda Jiang, Shenshen Wang
Format: Article
Language:English
Published: American Physical Society 2023-05-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/PhysRevX.13.021022