PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways

PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways

Introduction Endothelial progenitor cells (EPCs) dysfunction is involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). The transcription factor PU.1 is essential for the maintenance of stem/progenitor cell homeostasis. However, the role of PU.1 in COPD and its effects on EPC f...

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Bibliographic Details
Main Authors: Xue He<sup>+</sup>, Yanan Cui<sup>+</sup>, Tiao Li, Lijuan Luo, Zihang Zeng, Yiming Ma, Yan Chen
Format: Article
Language:English
Published: European Publishing 2024-01-01
Series:Tobacco Induced Diseases
Subjects:
pu.1
cigarette smoke extract
endothelial progenitor cell
wnt/β-catenin pathway
cxcl12/cxcr4 axis
Online Access:https://www.tobaccoinduceddiseases.org/PU-1-alleviates-the-inhibitory-effects-of-cigarette-smoke-non-endothelial-progenitor,174661,0,2.html

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https://www.tobaccoinduceddiseases.org/PU-1-alleviates-the-inhibitory-effects-of-cigarette-smoke-non-endothelial-progenitor,174661,0,2.html

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