Changes in the Plasma and Platelet Nitric Oxide Biotransformation Metabolites during Ischemic Stroke—A Dynamic Human LC/MS Metabolomic Study

Changes in the Plasma and Platelet Nitric Oxide Biotransformation Metabolites during Ischemic Stroke—A Dynamic Human LC/MS Metabolomic Study

Despite improvement in the management of modifiable cardiovascular risk factors, ischemic stroke remains the leading cause of morbidity and mortality in the adult population. The aim of this study was to analyze the time-dependent dynamic differences in expression of the nitric oxide (NO) metabolic...

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Bibliographic Details
Main Authors: Maciej Bladowski, Ewa Szahidewicz-Krupska, Jerzy Wiśniewski, Paulina Fortuna, Justyna Chojdak-Łukasiewicz, Slawomir Budrewicz, Mariusz Fleszar, Adrian Doroszko
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Antioxidants
Subjects:
ischemic stroke
platelet nitric oxide
L-Arginine
asymmetric dimethylarginine (ADMA)
acetylsalicylic acid
platelet aggregation
Online Access:https://www.mdpi.com/2076-3921/11/5/955

Internet

https://www.mdpi.com/2076-3921/11/5/955

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