Citreoviridin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis in Human Liver HepG2 Cells

Citreoviridin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis in Human Liver HepG2 Cells

Citreoviridin (CIT) is a mycotoxin derived from fungal species in moldy cereals. In our previous study, we reported that CIT stimulated autophagosome formation in human liver HepG2 cells. Here, we aimed to explore the relationship of autophagy with lysosomal membrane permeabilization and apoptosis i...

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Bibliographic Details
Main Authors: Yuexia Wang, Yanan Liu, Xiaofang Liu, Liping Jiang, Guang Yang, Xiance Sun, Chengyan Geng, Qiujuan Li, Xiaofeng Yao, Min Chen
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Toxins
Subjects:
citreoviridin
autophagy
apoptosis
lysosomal membrane permeabilization
human liver HepG2 cells
Online Access:http://www.mdpi.com/2072-6651/7/8/3030

Internet

http://www.mdpi.com/2072-6651/7/8/3030

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