Drug like HSP27 cross linkers with chromenone structure ameliorates pulmonary fibrosis

Drug like HSP27 cross linkers with chromenone structure ameliorates pulmonary fibrosis

Background: Pulmonary fibrosis (PF) is a progressive lung disease characterized by fibroblast accumulation and collagen deposition, resulting in lung scarring and impaired gas exchange. Current treatments for idiopathic pulmonary fibrosis (IPF) have limited efficacy and significant side effects. Hea...

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Bibliographic Details
Main Authors: Young Jo Yoo, Seulgi Jeon, Hee Jin, Hee Yeon Won, Mi Gyeong Jeong, Yeseul Cho, Eun Sook Hwang, Younghwa Na, Jaeho Cho, Yun-Sil Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Pharmacology
Subjects:
heat shock protein 27
cross linking inhibitors
NA49
pulmonary fibrosis
radiation
bleomycin
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1203033/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1203033/full

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