VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms

Summary: Consisting of three signaling pathways, the unfolded protein response (UPR) can be either protective or detrimental to cells that undergo ER stress. Elaborate regulation of the UPR is key to the cell-fate decision, but how it is achieved remains vague. Here, by studying cells deficient in v...

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Bibliographic Details
Main Authors: Tao Li, Hongyu Zhao, Gaofeng Guo, Shuwei Xia, Likun Wang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723002206