Total Mechanical Unloading Minimizes Metabolic Demand of Left Ventricle and Dramatically Reduces Infarct Size in Myocardial Infarction.

Total Mechanical Unloading Minimizes Metabolic Demand of Left Ventricle and Dramatically Reduces Infarct Size in Myocardial Infarction.

Left ventricular assist device (LVAD) mechanically unloads the left ventricle (LV). Theoretical analysis indicates that partial LVAD support (p-LVAD), where LV remains ejecting, reduces LV preload while increases afterload resulting from the elevation of total cardiac output and mean aortic pressure...

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Bibliographic Details
Main Authors: Keita Saku, Takamori Kakino, Takahiro Arimura, Takafumi Sakamoto, Takuya Nishikawa, Kazuo Sakamoto, Masataka Ikeda, Takuya Kishi, Tomomi Ide, Kenji Sunagawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4849631?pdf=render

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http://europepmc.org/articles/PMC4849631?pdf=render

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