Regio- and stereoselective synthesis of new spiro-isoxazolidines via 1,3-dipolar cycloaddition

Regio- and stereoselective synthesis of new spiro-isoxazolidines via 1,3-dipolar cycloaddition

New spiro-isoquinolinediones were prepared by regio- and stereoselective 1,3-dipolar cycloaddition of (E)-4-arylidene-N-methyl-isoquinoline-1,3-dione derivatives 1a–d with C-aryl-N-phenylnitrones 2e–g. NMR studies confirmed that only one regioisomer was formed selectively in the majority of cases. R...

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Bibliographic Details
Main Authors: Nafâa Jegham, Amira Bahi, Nizar El Guesmi, Yakdhane Kacem, Béchir Ben Hassine
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Arabian Journal of Chemistry
Subjects:
1,3-Dipolar cycloaddition
Isoquinolinediones
Nitrones
Regiochemistry
Stereoselective
Spiroisoxazolidines
Online Access:http://www.sciencedirect.com/science/article/pii/S187853521400104X

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http://www.sciencedirect.com/science/article/pii/S187853521400104X

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