Molecular characterization of human HSPCs with different cell fates in vivo using single‐cell transcriptome analysis and lentiviral barcoding technology

Molecular characterization of human HSPCs with different cell fates in vivo using single‐cell transcriptome analysis and lentiviral barcoding technology

Abstract Hematopoietic stem and progenitor cells (HSPCs) possess the potential to produce all types of blood cells throughout their lives. It is well recognized that HSPCs are heterogeneous, which is of great significance for their clinical applications and the treatment of diseases associated with...

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Bibliographic Details
Main Authors: Junnan Hua, Ke Wang, Yue Chen, Xiaojing Xu, Guoyi Dong, Yue Li, Rui Liu, Yecheng Xiong, Jiabin Ding, Tingting Zhang, Xinru Zeng, Yuxi Li, Haixi Sun, Ying Gu, Sixi Liu, Wenjie Ouyang, Chao Liu
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Clinical and Translational Medicine
Subjects:
barcoding technology
hematopoietic stem and progenitor cells
lineage tracing
scRNA‐seq
Online Access:https://doi.org/10.1002/ctm2.70085

Internet

https://doi.org/10.1002/ctm2.70085

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