Histone lactylation promotes malignant progression by facilitating USP39 expression to target PI3K/AKT/HIF-1α signal pathway in endometrial carcinoma

Histone lactylation promotes malignant progression by facilitating USP39 expression to target PI3K/AKT/HIF-1α signal pathway in endometrial carcinoma

Abstract Histone lactylation has been reported to involve in tumorigenesis and development. However, its biological regulatory mechanism in endometrial carcinoma (EC) is yet to be reported in detail. In the present study, we evaluated the modification levels of global lactylation in EC tissues by im...

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Bibliographic Details
Main Authors: Sitian Wei, Jun Zhang, Rong Zhao, Rui Shi, Lanfen An, Zhicheng Yu, Qi Zhang, Jiarui Zhang, Yuwei Yao, Haojia Li, Hongbo Wang
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01898-4

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https://doi.org/10.1038/s41420-024-01898-4

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