Exploiting viral sensing mediated by Toll-like receptors to design innovative vaccines
Abstract Toll-like receptors (TLRs) are transmembrane proteins belonging to the family of pattern-recognition receptors. They function as sensors of invading pathogens through recognition of pathogen-associated molecular patterns. After their engagement by microbial ligands, TLRs trigger downstream...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-10-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-021-00391-8 |