Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes

Local mechanical properties are important to cellular function; but conventional measurement techniques are limited in intact, living, 3D tissues. Here, the authors report on swellable hydrogel microparticles to monitor mechanical properties in situ via a temperature change.

Bibliographic Details
Main Authors: Stephanie Mok, Sara Al Habyan, Charles Ledoux, Wontae Lee, Katherine N. MacDonald, Luke McCaffrey, Christopher Moraes
Format: Article
Language:English
Published: Nature Portfolio 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18469-7