Quantitative 3D correlative light and electron microscopy of organelle association during autophagy

In macroautophagy, disk-shaped double-membrane structures called phagophores elongate to form cup-shaped structures, becoming autophagosomes upon closure. These autophagosomes then fuse with lysosomes to become autolysosomes and degrade engulfed material. Autophagosome formation is reported to invol...

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Bibliographic Details
Main Authors: Satoru Takahashi, Chieko Saito, Ikuko Koyama-Honda, Noboru Mizushima
Format: Article
Language:English
Published: Japan Society for Cell Biology 2022-11-01
Series:Cell Structure and Function
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/csf/47/2/47_22071/_html/-char/en