The Sea Anemone Neurotoxins Modulating Sodium Channels: An Insight at Structure and Functional Activity after Four Decades of Investigation

The Sea Anemone Neurotoxins Modulating Sodium Channels: An Insight at Structure and Functional Activity after Four Decades of Investigation

Many human cardiovascular and neurological disorders (such as ischemia, epileptic seizures, traumatic brain injury, neuropathic pain, etc.) are associated with the abnormal functional activity of voltage-gated sodium channels (VGSCs/Na<sub>V</sub>s). Many natural toxins, including the se...

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Bibliographic Details
Main Authors: Margarita Mikhailovna Monastyrnaya, Rimma Sergeevna Kalina, Emma Pavlovna Kozlovskaya
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Toxins
Subjects:
sea anemone
neurotoxins of types 1–4
voltage-gated sodium channels
electrophysiology
molecular modeling
Online Access:https://www.mdpi.com/2072-6651/15/1/8

Internet

https://www.mdpi.com/2072-6651/15/1/8

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