From Evaporative to Cooling Crystallisation: An Initial Co-Crystallisation Study of Cytosine and Its Fluorinated Derivative with 4-chloro-3,5-dinitrobenzoic Acid

From Evaporative to Cooling Crystallisation: An Initial Co-Crystallisation Study of Cytosine and Its Fluorinated Derivative with 4-chloro-3,5-dinitrobenzoic Acid

Two new multi-component molecular complexes of cytosine and 5-fluorocytosine with 4-chloro-3,5-dinitrobenzoic acid are presented. Materials synthesis was achieved initially by evaporative crystallisation and the crystal structures determined. The process was then successfully transferred into a cont...

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Bibliographic Details
Main Authors: Kate Wittering, Josh King, Lynne H. Thomas, Chick C. Wilson
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Crystals
Subjects:
molecular complexes
multi-component crystallisation
continuous manufacturing and crystallisation
cooling crystallisation
process analytical technologies
turbidity measurements
Online Access:http://www.mdpi.com/2073-4352/4/2/123

Internet

http://www.mdpi.com/2073-4352/4/2/123

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