Human Lung-Resident Macrophages Express and Are Targets of Thymic Stromal Lymphopoietin in the Tumor Microenvironment

Human Lung-Resident Macrophages Express and Are Targets of Thymic Stromal Lymphopoietin in the Tumor Microenvironment

Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine highly expressed by epithelial cells and several innate and adaptive immune cells. TSLP exerts its biological effects by binding to a heterodimeric complex composed of TSLP receptor (TSLPR) and IL-7Rα. In humans, there are two TSLP isofor...

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Bibliographic Details
Main Authors: Mariantonia Braile, Alfonso Fiorelli, Daniela Sorriento, Rosa Maria Di Crescenzo, Maria Rosaria Galdiero, Gianni Marone, Mario Santini, Gilda Varricchi, Stefania Loffredo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
angiogenesis
lymphangiogenesis
lung cancer
macrophages
monocytes
monocyte-derived macrophages
Online Access:https://www.mdpi.com/2073-4409/10/8/2012

Internet

https://www.mdpi.com/2073-4409/10/8/2012

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