A new pipeline SPICE identifies novel JUN-IKZF1 composite elements
Transcription factor partners can cooperatively bind to DNA composite elements to augment gene transcription. Here, we report a novel protein-DNA binding screening pipeline, termed Spacing Preference Identification of Composite Elements (SPICE), that can systematically predict protein binding partne...
Main Authors: | , , , , , , |
---|---|
格式: | Article |
語言: | English |
出版: |
eLife Sciences Publications Ltd
2025-01-01
|
叢編: | eLife |
主題: | |
在線閱讀: | https://elifesciences.org/articles/88833 |