Search of inhibitors of aldose reductase for treatment of diabetic cataracts using machine learning

Purpose: Patients with diabetes mellitus have an elevated chance of developing cataracts, a degenerative vision-impairing condition often needing surgery. The process of the reduction of glucose to sorbitol in the lens of the human eye that causes cataracts is managed by the Aldose Reductase Enzyme...

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Bibliographic Details
Main Authors: Trevor Chen, Richard Chen, Alvin You, Valentina L. Kouznetsova, Igor F. Tsigelny
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Advances in Ophthalmology Practice and Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667376223000306