Long QT Syndrome Type 2: Emerging Strategies for Correcting Class 2 <i>KCNH2</i> (<i>hERG</i>) Mutations and Identifying New Patients

Long QT Syndrome Type 2: Emerging Strategies for Correcting Class 2 <i>KCNH2</i> (<i>hERG</i>) Mutations and Identifying New Patients

Significant advances in our understanding of the molecular mechanisms that cause congenital long QT syndrome (LQTS) have been made. A wide variety of experimental approaches, including heterologous expression of mutant ion channel proteins and the use of inducible pluripotent stem cell-derived cardi...

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Bibliographic Details
Main Authors: Makoto Ono, Don E. Burgess, Elizabeth A. Schroder, Claude S. Elayi, Corey L. Anderson, Craig T. January, Bin Sun, Kalyan Immadisetty, Peter M. Kekenes-Huskey, Brian P. Delisle
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomolecules
Subjects:
long QT syndrome
ion channel
trafficking
<i>KCNH2</i>
<i>hERG</i>
Online Access:https://www.mdpi.com/2218-273X/10/8/1144

Internet

https://www.mdpi.com/2218-273X/10/8/1144

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