Physiologically Based Pharmacokinetic (PBPK) model for biodistribution of radiolabeled peptides in patients with neuroendocrine tumours

Objective(s): The objectives of this work was to assess the benefits of the application of Physiologically Based Pharmacokinetic (PBPK) models in patients with different neuroendocrine tumours (NET) who were treatedwith Lu-177 DOTATATE. The model utilises clinical data on biodistribution of radiolab...

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Bibliographic Details
Main Authors: Viktor Popov, Radovan Gospavic, Peter Knoll, Siroos Mirzaei
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-07-01
Series:Asia Oceania Journal of Nuclear Medicine and Biology
Subjects:
Online Access:http://aojnmb.mums.ac.ir/article_7006_0857d44d3337524867489f5b317647d6.pdf