Lipopolysaccharide-deficient Brucella variants arise spontaneously during infection

Lipopolysaccharide-deficient mutants of smooth Brucella species (rough mutants) have been shown to arise spontaneously in culture. However, in situ analysis of Brucella infected macrophages using antibody directed against O-polysaccharide suggested a loss of reactivity of Brucella consistent with th...

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Bibliographic Details
Main Authors: Joshua E. Turse, Jianwu ePei, Thomas A Ficht
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00054/full