Comparative Effectiveness of Combined IgM-Enriched Immunoglobulin and Extracorporeal Blood Purification Plus Standard Care Versus Standard Care for Sepsis and Septic Shock after Cardiac Surgery

Comparative Effectiveness of Combined IgM-Enriched Immunoglobulin and Extracorporeal Blood Purification Plus Standard Care Versus Standard Care for Sepsis and Septic Shock after Cardiac Surgery

Background: The combination of surgery, bacterial spread-out, and artificial cardiopulmonary bypass surfaces results in a release of key inflammatory mediators leading to an overshooting systemic hyper-inflammatory condition frequently associated with compromised hemodynamics and organ dysfunction....

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Bibliographic Details
Main Authors: Gianluca Paternoster, Silvia De Rosa, Pietro Bertini, Pasquale Innelli, Rosaria Vignale, Vincenzo Francesco Tripodi, Giuseppe Buscaglia, Mariacristina Vadalà, Michele Rossi, Antonio Arena, Andrea Demartini, Giovanni Tripepi, Domenico Abelardo, Giuseppe Pittella, Aldo Di Fazio, Sabino Scolletta, Fabio Guarracino, Blanca Martinez Lopez de Arroyabe
Format: Article
Language:English
Published: IMR Press 2022-09-01
Series:Reviews in Cardiovascular Medicine
Subjects:
blood purification therapy
cardiac surgery
igm-enriched immunoglobulin
sepsis
pentaglobin
hyper-inflammation
immunosuppression
Online Access:https://www.imrpress.com/journal/RCM/23/9/10.31083/j.rcm2309314

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https://www.imrpress.com/journal/RCM/23/9/10.31083/j.rcm2309314

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