The Cholesterol Metabolite Cholest-5-en-3-One Alleviates Hyperglycemia and Hyperinsulinemia in Obese (<i>db</i>/<i>db</i>) Mice

The Cholesterol Metabolite Cholest-5-en-3-One Alleviates Hyperglycemia and Hyperinsulinemia in Obese (<i>db</i>/<i>db</i>) Mice

Dietary sterols are catabolized into various substances in the intestinal tract. Dietary 3-oxo derivatives of cholesterol and plant sterols (e.g., cholest-4-en-3-one and campest-5-en-3-one) have been shown to have anti-obesity effects. In this study, we tested whether feeding cholest-5-en-3-one (5-c...

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Bibliographic Details
Main Authors: Koji Nagao, Nao Inoue, Kunio Suzuki, Takeshi Shimizu, Teruyoshi Yanagita
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Metabolites
Subjects:
5-cholestenone
hyperglycemia
hyperinsulinemia
inflammation
obese <i>db</i>/<i>db</i> mouse
Online Access:https://www.mdpi.com/2218-1989/12/1/26

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https://www.mdpi.com/2218-1989/12/1/26

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