An Examination of the Effect of Aspirin and Salicylic Acid on Soluble Fms-like Tyrosine Kinase-1 Release from Human Placental Trophoblasts

An Examination of the Effect of Aspirin and Salicylic Acid on Soluble Fms-like Tyrosine Kinase-1 Release from Human Placental Trophoblasts

Low-dose aspirin (LDA) is efficacious in preventing preeclampsia, but its mechanism of action is unclear. Conflicting evidence suggests that it may inhibit placental trophoblast release of soluble fms-like tyrosine kinase-1 (sFlt1), a key mediator of preeclampsia. We examined whether, and at what co...

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Bibliographic Details
Main Authors: Jiawu Zhao, Rui Duan, Jinghui Sun, Rebecca P. Chow, Timothy J. Lyons, Jeremy Y. Yu
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cells
Subjects:
aspirin
hypoxia
preeclampsia
salicylic acid
soluble fms-like tyrosine kinase-1
trophoblast
Online Access:https://www.mdpi.com/2073-4409/13/2/113

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https://www.mdpi.com/2073-4409/13/2/113

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