<i>Acinetobacter baumannii</i> under Acidic Conditions Induces Colistin Resistance through PmrAB Activation and Lipid A Modification

Colistin is a last-resort antimicrobial agent for treating carbapenem-resistant <i>Acinetobacter baumannii</i> infections. The activation of PmrAB by several environmental signals induces colistin resistance in Gram-negative bacteria. This study investigated the molecular mechanisms of c...

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Bibliographic Details
Main Authors: Seo-Yeon Ko, Nayeong Kim, Seong-Yong Park, Seong-Yeop Kim, Minsang Shin, Je-Chul Lee
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/12/5/813