Expression of GCaMP6s in the dentate gyrus induces tonic–clonic seizures

Expression of GCaMP6s in the dentate gyrus induces tonic–clonic seizures

Abstract GCaMP is a genetically encoded calcium indicator (GECI) widely used in neuroscience research. It measures intracellular Ca2+ level by fluorescence changes as it directly binds to Ca2+. In this process, the effect of this calcium buffer on the intracellular calcium signaling and cell physiol...

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Bibliographic Details
Main Authors: Sasa Teng, Wanqi Wang, Jia Jun Joel Wen, Jingxuan Wang, Gergely F. Turi, Yueqing Peng
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Seizures
Dentate gyrus
GCaMP6s
Ca2+
EEG
Online Access:https://doi.org/10.1038/s41598-024-58819-9

Internet

https://doi.org/10.1038/s41598-024-58819-9

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