A comparison of DNA methylation in newborn blood samples from infants with and without orofacial clefts

A comparison of DNA methylation in newborn blood samples from infants with and without orofacial clefts

Abstract Background Isolated orofacial clefts are among the most common congenital birth defects. Although the underlying biological mechanisms remain largely unknown, clefts are thought to be complex disorders influenced by genetic, environmental, and potentially epigenetic factors. Methods In bloo...

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Bibliographic Details
Main Authors: Zongli Xu, Rolv T. Lie, Allen J. Wilcox, Ola Didrik Saugstad, Jack A. Taylor
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Cleft lip
Cleft palate
Blood
Newborns
Online Access:http://link.springer.com/article/10.1186/s13148-019-0638-9

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http://link.springer.com/article/10.1186/s13148-019-0638-9

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