HLA Expression Correlates to the Risk of Immune Checkpoint Inhibitor-Induced Pneumonitis

HLA Expression Correlates to the Risk of Immune Checkpoint Inhibitor-Induced Pneumonitis

Tumor-infiltrating T cell rescue by programmed cell death receptor-1 (PD-1)/PD-1 ligand-1 (PD-L1) immune checkpoint blockade is a recommended treatment for malignant diseases, including metastatic non-small-cell lung cancer (mNSCLC), malignant melanoma (MM), head and neck, kidney, and urothelial can...

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Bibliographic Details
Main Authors: Pierpaolo Correale, Rita Emilena Saladino, Diana Giannarelli, Andrea Sergi, Maria Antonietta Mazzei, Giovanna Bianco, Rocco Giannicola, Eleonora Iuliano, Iris Maria Forte, Natale Daniele Calandruccio, Antonia Consuelo Falzea, Alessandra Strangio, Valerio Nardone, Pierpaolo Pastina, Paolo Tini, Amalia Luce, Michele Caraglia, Daniele Caracciolo, Luciano Mutti, Pierfrancesco Tassone, Luigi Pirtoli, Antonio Giordano, Pierosandro Tagliaferri
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
cancer immunotherapy
PD-1/PD-L1 blockade
irAEs
immune-related pneumonitis
HLA-profile
Online Access:https://www.mdpi.com/2073-4409/9/9/1964

Internet

https://www.mdpi.com/2073-4409/9/9/1964

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