Oral nano-formulation improves pancreatic islets dysfunction via lymphatic transport for antidiabetic treatment

Type 2 diabetes mellitus (T2DM) therapy is facing the challenges of long-term medication and gradual destruction of pancreatic islet β-cells. Therefore, it is timely to develop oral prolonged action formulations to improve compliance, while restoring β-cells survival and function. Herein, we designe...

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Bibliographic Details
Main Authors: Lin Hou, Xueyuan Peng, Ruiting Wang, Yifei Wang, Hong Li, Huijuan Zhang, Yun Zhang, Zhenzhong Zhang
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522005238