Distinct p53 phosphorylation patterns in chronic lymphocytic leukemia patients are reflected in the activation of circumjacent pathways upon DNA damage

Distinct p53 phosphorylation patterns in chronic lymphocytic leukemia patients are reflected in the activation of circumjacent pathways upon DNA damage

TP53 gene abnormalities represent the most important biomarker in chronic lymphocytic leukemia (CLL). Altered protein modifications could also influence p53 function, even in the wild‐type protein. We assessed the impact of p53 protein phosphorylations on p53 functions as an alternative inactivation...

Full description

Bibliographic Details
Main Authors: Veronika Mancikova, Michaela Pesova, Sarka Pavlova, Robert Helma, Kristyna Zavacka, Vaclav Hejret, Petr Taus, Jakub Hynst, Karla Plevova, Jitka Malcikova, Sarka Pospisilova
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Molecular Oncology
Subjects:
CLL
p53
phosphorylation
Online Access:https://doi.org/10.1002/1878-0261.13337

Internet

https://doi.org/10.1002/1878-0261.13337

Similar Items