Evaluation of the PSMA-Binding Ligand <sup>212</sup>Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer

Evaluation of the PSMA-Binding Ligand <sup>212</sup>Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer

Radioligand therapy targeting the prostate-specific membrane antigen (PSMA) is rapidly evolving as a promising treatment for metastatic castration-resistant prostate cancer. The PSMA-targeting ligand p-SCN-Bn-TCMC-PSMA (NG001) labelled with <sup>212</sup>Pb efficiently targets PSMA-posit...

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Bibliographic Details
Main Authors: Vilde Yuli Stenberg, Roy Hartvig Larsen, Li-Wei Ma, Qian Peng, Petras Juzenas, Øyvind Sverre Bruland, Asta Juzeniene
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
prostate-specific membrane antigen
metastatic castration-resistant prostate cancer
targeted alpha therapy
p-SCN-Bn-TCMC-PSMA ligand (NG001)
<sup>212</sup>Pb
Online Access:https://www.mdpi.com/1422-0067/22/9/4815

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https://www.mdpi.com/1422-0067/22/9/4815

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