Variations in the Human Serum Albumin Gene: Molecular and Functional Aspects

Variations in the Human Serum Albumin Gene: Molecular and Functional Aspects

The human albumin gene, the most abundant serum protein, is located in the long arm of chromosome 4, near the centromere, position 4q11–3. It is divided by 14 intervening introns into 15 exons, the last of which is untranslated. To date, 74 nucleotide substitutions (mainly missense) have been report...

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Bibliographic Details
Main Authors: Gianluca Caridi, Francesca Lugani, Andrea Angeletti, Monica Campagnoli, Monica Galliano, Lorenzo Minchiotti
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
genetic variants
structural changes
stability: ligand binding
pharmacokinetics
congenital analbuminaemia
Online Access:https://www.mdpi.com/1422-0067/23/3/1159

Internet

https://www.mdpi.com/1422-0067/23/3/1159

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