Combination of Virtual Screening Protocol by in Silico toward the Discovery of Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

4-Hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, HPPD) is a potent new bleaching herbicide target. Therefore, in silico structure-based virtual screening was performed in order to speed up the identification of promising HPPD inhibitors. In this study, an integrated virtual screening protocol by...

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Bibliographic Details
Main Authors: Ying Fu, Yi-Na Sun, Ke-Han Yi, Ming-Qiang Li, Hai-Feng Cao, Jia-Zhong Li, Fei Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2018.00014/full