Bioactivity-Guided Separation of Anti-Cholinesterase Alkaloids from <i>Uncaria rhynchophlly</i> (Miq.) Miq. Ex Havil Based on HSCCC Coupled with Molecular Docking

Bioactivity-Guided Separation of Anti-Cholinesterase Alkaloids from <i>Uncaria rhynchophlly</i> (Miq.) Miq. Ex Havil Based on HSCCC Coupled with Molecular Docking

As an important source of cholinesterase inhibitors, alkaloids in natural products have high potential value in terms of exerting pharmacological activities. In this study, a strategy for targeted preparation of cholinesterase inhibitors in <i>Uncaria rhynchophlly</i> (Miq.) Miq. ex Havi...

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Bibliographic Details
Main Authors: Pengfei Yu, Zhenshan Chen, Yuecheng Liu, Zhengwei Gu, Xiaoming Wang, Yaowen Zhang, Yanni Ma, Meiyue Dong, Zhenhua Tian
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
<i>Uncaria rhynchophlly</i> (Miq.) Miq. ex Havil
HSCCC
alkaloids
cholinesterase inhibitory activity
Online Access:https://www.mdpi.com/1420-3049/27/6/2013

Internet

https://www.mdpi.com/1420-3049/27/6/2013

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