Retinoids Promote Mouse Bone Marrow-Derived Macrophage Differentiation and Efferocytosis via Upregulating Bone Morphogenetic Protein-2 and Smad3

Retinoids Promote Mouse Bone Marrow-Derived Macrophage Differentiation and Efferocytosis via Upregulating Bone Morphogenetic Protein-2 and Smad3

Clearance of apoptotic cells by bone marrow-derived macrophages differentiated from monocytes plays a central role in the resolution of inflammation, as the conversion of pro-inflammatory M1 macrophages to M2 macrophages that mediate the resolution process occurs during efferocytosis. Thus, proper e...

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Bibliographic Details
Main Authors: Éva Fige, Zsolt Sarang, László Sós, Zsuzsa Szondy
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
macrophage differentiation
BMP-2
Smad3
efferocytosis
retinoids
inflammation
Online Access:https://www.mdpi.com/2073-4409/11/18/2928

Internet

https://www.mdpi.com/2073-4409/11/18/2928

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