Towards Standardisation of a Diffuse Midline Glioma Patient-Derived Xenograft Mouse Model Based on Suspension Matrices for Preclinical Research

Towards Standardisation of a Diffuse Midline Glioma Patient-Derived Xenograft Mouse Model Based on Suspension Matrices for Preclinical Research

Diffuse midline glioma (DMG) is an aggressive brain tumour with high mortality and limited clinical therapeutic options. Although in vitro research has shown the effectiveness of medication, successful translation to the clinic remains elusive. A literature search highlighted the high variability an...

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Bibliographic Details
Main Authors: Elvin ’t Hart, John Bianco, Helena C. Besse, Lois A. Chin Joe Kie, Lesley Cornet, Kimberly L. Eikelenboom, Thijs J.M. van den Broek, Marc Derieppe, Yan Su, Eelco W. Hoving, Mario G. Ries, Dannis G. van Vuurden
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
HSJD-DIPG-007
diffuse midline glioma
PDX model
Matrigel
metastases
Online Access:https://www.mdpi.com/2227-9059/11/2/527

Internet

https://www.mdpi.com/2227-9059/11/2/527

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