Disease progression in proposed brain-first and body-first Parkinson’s disease subtypes

Abstract A new Parkinson’s disease (PD) subtyping model has been recently proposed based on the initial location of α-synuclein inclusions, which divides PD patients into the brain-first subtype and the body-first subtype. Premotor RBD has proven to be a predictive marker of the body-first subtype....

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Bibliographic Details
Main Authors: Zhiheng Xu, Tianyu Hu, Chenqin Xu, Xiaoniu Liang, Shiyu Li, Yimin Sun, Fengtao Liu, Jian Wang, Yilin Tang
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-024-00730-1