Conditional deletion of Ccl2 in smooth muscle cells does not reduce early atherosclerosis in mice
Background and aims: C–C motif chemokine ligand 2 (CCL2) is a pro-inflammatory chemokine important for monocyte recruitment to the arterial wall and atherosclerotic plaques. Global knockout of Ccl2 reduces plaque formation and macrophage content in mice, but the importance of different plaque cell t...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-03-01
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Series: | Atherosclerosis Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667089523000512 |