Association of candidate genetic variants and circulating levels of ApoE/ApoJ with common neuroimaging features of cerebral amyloid angiopathy

IntroductionCerebral amyloid angiopathy (CAA) is characterized by the accumulation of amyloid-β (Aβ) in brain vessels and is a main cause of lobar intracerebral hemorrhage (ICH) in the elderly. CAA is associated with magnetic resonance imaging (MRI) markers of small vessel disease (SVD). Since Aβ is...

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Main Authors: Anna Bonaterra-Pastra, Sònia Benítez, Olalla Pancorbo, David Rodríguez-Luna, Carla Vert, Alex Rovira, M. Mar Freijo, Silvia Tur, Maite Martínez-Zabaleta, Pere Cardona Portela, Rocío Vera, Lucia Lebrato-Hernández, Juan F. Arenillas, Soledad Pérez-Sánchez, Ana Domínguez-Mayoral, Joan Martí Fàbregas, Gerard Mauri, Joan Montaner, Jose Luis Sánchez-Quesada, Mar Hernández-Guillamon
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1134399/full