Human Serum Proteins and Susceptibility of <i>Acinetobacter baumannii</i> to Cefiderocol: Role of Iron Transport

Human Serum Proteins and Susceptibility of <i>Acinetobacter baumannii</i> to Cefiderocol: Role of Iron Transport

Cefiderocol, a recently introduced antibiotic, has a chemical structure that includes a cephalosporin that targets cell wall synthesis and a chlorocatechol siderophore moiety that facilitates cell penetration by active iron transporters. Analysis of the effect that human serum, human serum albumin,...

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Bibliographic Details
Main Authors: Casin Le, Camila Pimentel, Fernando Pasteran, Marisel R. Tuttobene, Tomás Subils, Jenny Escalante, Brent Nishimura, Susana Arriaga, Aimee Carranza, Vyanka Mezcord, Alejandro J. Vila, Alejandra Corso, Luis A. Actis, Marcelo E. Tolmasky, Robert A. Bonomo, Maria Soledad Ramírez
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomedicines
Subjects:
<i>Acinetobacter baumannii</i>
cefiderocol
human fluids
iron
human serum albumin
Online Access:https://www.mdpi.com/2227-9059/10/3/600

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https://www.mdpi.com/2227-9059/10/3/600

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