The winged helix domain of MORF binds CpG islands and the TAZ2 domain of p300

The winged helix domain of MORF binds CpG islands and the TAZ2 domain of p300

Summary: Acetylation of histones by lysine acetyltransferases (KATs) provides a fundamental mechanism by which chromatin structure and transcriptional programs are regulated. Here, we describe a dual binding activity of the first winged helix domain of human MORF KAT (MORFWH1) that recognizes the TA...

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Bibliographic Details
Main Authors: Dustin C. Becht, Akinori Kanai, Soumi Biswas, Mohamed Halawa, Lei Zeng, Khan L. Cox, Michael G. Poirier, Ming-Ming Zhou, Xiaobing Shi, Akihiko Yokoyama, Tatiana G. Kutateladze
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Biochemistry
Structural biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224005881

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http://www.sciencedirect.com/science/article/pii/S2589004224005881

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