Add‐on cannabidiol significantly decreases seizures in 3 patients with SYNGAP1 developmental and epileptic encephalopathy

Add‐on cannabidiol significantly decreases seizures in 3 patients with SYNGAP1 developmental and epileptic encephalopathy

Abstract Mutations in SYNGAP1 are associated with developmental delay, epilepsy, and autism spectrum disorder (ASD). Epilepsy is often drug‐resistant in this syndrome with frequent drop attacks. In a prospective study of add‐on cannabidiol (CBD), we identified three patients with SYNGAP1 mutations:...

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Bibliographic Details
Main Authors: Mathieu Kuchenbuch, Gianluca D'Onofrio, Nicole Chemaly, Giulia Barcia, Théo Teng, Rima Nabbout
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Epilepsia Open
Subjects:
atypical absence
drug‐resistant
efficacy
epileptic encephalopathy
myoclonic seizures
safety
Online Access:https://doi.org/10.1002/epi4.12411

Internet

https://doi.org/10.1002/epi4.12411

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