Scaling Up of Steric Exclusion Membrane Chromatography for Lentiviral Vector Purification

Lentiviral vectors (LVs) are widely used in clinical trials of gene and cell therapy. Low LV stability incentivizes constant development and the improvement of gentle process steps. Steric exclusion chromatography (SXC) has gained interest in the field of virus purification but scaling up has not ye...

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Bibliographic Details
Main Authors: Jennifer Julia Labisch, Richard Paul, G. Philip Wiese, Karl Pflanz
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/13/2/149