The tyrosine capsid mutations on retrograde adeno-associated virus accelerates gene transduction efficiency
Abstract Adeno-associated virus (AAV) vector is a critical tool for gene delivery through its durable transgene expression and safety profile. Among many serotypes, AAV2-retro is typically utilized for dissecting neural circuits with its retrograde functionality. However, this vector requires a rela...
| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
BMC
2022-08-01
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| coleção: | Molecular Brain |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s13041-022-00957-0 |