Different exposure modes of PM2.5 induces bronchial asthma and fibrosis in male rats through macrophage activation and immune imbalance induced by TIPE2 methylation

Different exposure modes of PM2.5 induces bronchial asthma and fibrosis in male rats through macrophage activation and immune imbalance induced by TIPE2 methylation

Exposure to PM2.5 can aggravate the occurrence and development of bronchial asthma and fibrosis. Here, we investigated the differences in bronchial injury caused by different exposure modes of PM2.5 (high concentration intermittent exposure and low concentration continuous exposure), and the mechani...

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Bibliographic Details
Main Authors: Huanliang Liu, Huipeng Nie, Wenqing Lai, Yue Shi, Xuan Liu, Kang Li, Lei Tian, Zhuge Xi, Bencheng Lin
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PM2.5
Bronchial asthma and fibrosis
Macrophage activation
TIPE2 DNA methylation
Immune imbalance
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322010405

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http://www.sciencedirect.com/science/article/pii/S0147651322010405

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