Ginsenoside Rb1 exerts therapeutic effects on ulcerative colitis through regulating the Nrf2/PIP2/NLRP3 inflammasome signaling pathway

Ginsenoside Rb1 exerts therapeutic effects on ulcerative colitis through regulating the Nrf2/PIP2/NLRP3 inflammasome signaling pathway

Ginsenoside Rb1 (GRb1), a bioactive ingredient of Panax ginseng C. A. Meyer, has the effects of anti-tumor, anti-inflammation, and cardiovascular protection. The present study aims to explore the effects and potential mechanisms of GRb1 on UC. GRb1 suppressed the secretion of tumor necrosis factor-α...

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Bibliographic Details
Main Authors: Siyuan Li, Renyikun Yuan, Qiumei Fan, Chunting Zhang, Shan Han, Jilang Li, Zhipeng Xu, Kaili Sun, Qiongming Xu, Chun Yao, Shilin Yang, Hongwei Gao
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of Functional Foods
Subjects:
Ginsenoside Rb1
Ulcerative colitis
Nrf2/PIP2/NLRP3 signaling pathway
Reactive oxygen species
Ca2+
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623000750

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http://www.sciencedirect.com/science/article/pii/S1756464623000750

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