Specific Methyl-CpG Configurations Define Cell Identity through Gene Expression Regulation

Specific Methyl-CpG Configurations Define Cell Identity through Gene Expression Regulation

Cell identity is determined by the chromatin structure and profiles of gene expression, which are dependent on chromatin accessibility and DNA methylation of the regions critical for gene expression, such as enhancers and promoters. These epigenetic modifications are required for mammalian developme...

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Bibliographic Details
Main Authors: Teresa Improda, Valentina Morgera, Maria Vitale, Lorenzo Chiariotti, Fabiana Passaro, Antonia Feola, Antonio Porcellini, Mariella Cuomo, Antonio Pezone
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
methyl-CpG
DNA methylation
gene expression
cell identity
Online Access:https://www.mdpi.com/1422-0067/24/12/9951

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https://www.mdpi.com/1422-0067/24/12/9951

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