Asymmetric Hydrogenation of Tetrasubstituted α,β-Unsaturated Ketones: Access to Chiral 2‑Substituted Cyclopentyl Aryl Ketones

Asymmetric Hydrogenation of Tetrasubstituted α,β-Unsaturated Ketones: Access to Chiral 2‑Substituted Cyclopentyl Aryl Ketones

Asymmetric hydrogenation of tetrasubstituted alkenes is an important but challenging research topic. Herein, we report an efficient iridium-catalyzed asymmetric hydrogenation of tetrasubstituted α,β-unsaturated ketones for the synthesis of chiral 2-substituted cyclopentyl aryl ketones, an important...

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Bibliographic Details
Main Authors: Zhengdong Ding, Feng Gao, Yining Lu, Qianjia Yuan, Wei-Ping Deng, Wanbin Zhang
Format: Article
Language:English
Published: American Chemical Society 2023-02-01
Series:Precision Chemistry
Online Access:https://doi.org/10.1021/prechem.2c00010

Internet

https://doi.org/10.1021/prechem.2c00010

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